MOULINVéronique Moulin, Ph.D.

Researcher,
Centre de Recherche en Organogénèse Expérimentale de l’Université Laval/ LOEX
CHU de Québec Research Center-Université Laval
Full Professor,
Department of Surgery within the Faculty of Medicine of Université Laval

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The research group on wound healing and tissue fibrosis was founded by Véronique Moulin in 1998 at the “Hôpital du Saint-Sacrement”. In 2010, following the construction of the CMDGT, in which she contributed very significantly, her group moved in 2010 at the CMDGT at the “Hôpital de l’Enfant-Jésus”. The work carried out by the group focused on the mechanisms of normal, but also pathological scarring. Among the problems related to healing, fibrosis is a very frequent process in burned individual, which result in significant morbidities. Projects developed with the support of the students and the research assistants of the laboratory focus on understanding the interactions between the cell and the tissues. Such interactions involve the production of cytokines and growth factors, but also the production of microparticles and exosomes by the cells in the wound. To investigate this, different cell culture models, produced by tissue engineering, give us the possibility of mimicking fibrotic diseases of the skin (hypertrophic scarring, scleroderma) in vitro. The goal of understanding these mechanisms is to identify new treatments to prevent or cure the formation of hypertrophic scars and scleroderma. In addition to this research, the clinical application of tissue engineering in the context of problematic scarring (extended burns, hypertrophic scars) is developed through the implementation of clinical trials in patients.
Dr. Véronique Moulin received her doctorate in Biology, Physical Chemistry and Molecular Pharmacology at Paris, France, in 1993. She then completed a postdoctoral fellowship in tissue engineering in the laboratory of Dr. Lucie Germain at LOEX. In 1998, she became a professor at Université Laval in the Department of Surgery and founded the research group on wound healing and tissue fibrosis at the LOEX. Since her beginnings in research, she has authored nearly 50 publications and she has been invited to many international conferences while organizing several meetings and scientific symposia.
Over the years, the group has welcomed many people (18 master’s students, 4 PhD students, 1 post-doc; 36 trainees and 2 research assistants), whom I thank for their hard work and their ability to transform work into a daily pleasure. Their dynamism, their love of science and their personal qualities are greatly appreciated.