Lucie Germain

Publications récentes

Cantin-Warren L, Guignard R, Cortez Ghio S, Larouche D, Auger FA, Germain L. Specialized Living Wound Dressing Based on the Self-Assembly Approach of Tissue Engineering.  J Funct Biomater, 9 (3), 2018, ISSN: 2079-4983.

Germain L, Larouche D, Nedelec B, Perreault I, Duranceau L, Bortoluzzi P, Beaudoin Cloutier C, Genest H, Caouette-Laberge L, Dumas A, Bussiere A, Boghossian E, Kanevsky J, Leclerc Y, Lee J, Nguyen MT, Bernier V, Knoppers BM, Moulin VJ, Auger FA. Autologous bilayered self-assembled skin substitutes (SASSs) as permanent grafts: a case series of 14 severely burned patients indicating clinical effectiveness.  Eur Cell Mater, 36 , p. 128-141, 2018.

Cortez Ghio S, Cantin-Warren L, Guignard R, Larouche D, Germain L. Are the Effects of the Cholera Toxin and Isoproterenol on Human Keratinocytes' Proliferative Potential Dependent on Whether They Are Co-Cultured with Human or Murine Fibroblast Feeder Layers?  Int J Mol Sci, 19 (8), 2018.

Le-Bel G, Giasson CJ, Deschambeault A, Carrier P, Germain L, Guerin S. LThe presence of a feeder layer improves human corneal endothelial cell proliferation by altering the expression of the transcription factors Sp1 and NFI.  Exp Eye Res, 176 , p. 161-173, 2018, ISSN: 0014-4835.

Couture C, Desjardins P, Zaniolo K, Germain L, Guerin SL. Enhanced wound healing of tissue-engineered human corneas through altered phosphorylation of the CREB and AKT signal transduction pathways.  Acta Biomater, 73 , p. 312-325, 2018, ISSN: 1742-7061.

Le-Bel G, Ghio SC, Larouche D, Germain L, Guerin SLQualitatively Monitoring Binding and Expression of the Transcription Factors Sp1 and NFI as a Useful Tool to Evaluate the Quality of Primary Cultured Epithelial Stem Cells in Tissue Reconstruction.  Methods Mol Biol, 2018, ISSN: 1064-3745.

Dakiw Piaceski A, Larouche D, Ghani K, Bisson F, Cortez Ghio S, Larochelle S, Moulin MJ, Caruso M, Germain L. Translating the combination of gene therapy and tissue engineering for treating recessive dystrophic epidermolysis bullosa.  Eur Cell Mater, 35 , p. 73-86, 2018.

Bourget JM, Laterreur V, Gauvin R, Guillemette MD, Miville-Godin C, Mounier M, Tondreau MY, Tremblay C, Labbe R, Ruel J, Auger FA, Veres T, Germain L. Microstructured human fibroblast-derived extracellular matrix scaffold for vascular media fabrication.  J Tissue Eng Regen Med, 11 (9), p. 2479-2489, 2017, ISSN: 1932-6254.

Mao J, Wang Y, Philippe E, Cianciulli T, Vesely I, How D, Bourget JM, Germain L, Zhang Z, Guidoin R. Microstructural alterations owing to handling of bovine pericardium to manufacture bioprosthetic heart valves: A potential risk for cusp dehiscence.  Morphologie, 101 (333), p. 77-87, 2017, ISSN: 1286-0115

Bourget JM, Zegdi R, Lin J, Wawryko P, Merhi Y, Convelbo C, Mao J, Fu Y, Xu T, Merkel NO, Wang L, Germain L, Zhang Z, Guidoin R. Correlation between structural changes and acute thrombogenicity in transcatheter pericardium valves after crimping and balloon deployment.  Morphologie, 101 (332), p. 19-32, 2017, ISSN: 1286-0115.

Picard-Deland M., Ruel J., Galbraith T., Tremblay C., Kawecki F., Germain L., Auger FA. Tissue-Engineered tubular heart valves combining a novel precontraction phase with the self-assembly method". Annals of Biomedical Engineering, 2016.

Tondreau MY., Laterreur V., Vallières K., Gauvin R., Bourget JM., Tremblay C., Lacroix D., Germain L., Ruel J., Auger FA. In vivo remodeling of fibroblast-derived vascular scaffolds implanted for 6 months in rats. BioMed Research International, p. 3762484, 2016.

Simard-Bisson C, Bidoggia J, Larouche D, Guerin SL, Blouin R, Hirai SI, Germain L. A Role for DLK in Microtubule Reorganization to the Cell Periphery and in the Maintenance of Desmosomal and Tight Junction Integrity.  J Invest Dermatol, 137 (1), p. 132-141, 2017, ISSN: 0022-202X.

Beaudoin Cloutier C, Goyer B, Perron C, Guignard R, Larouche D, Moulin VJ, Germain L, Gauvin R, Auger FA. In Vivo Evaluation and Imaging of a Bilayered Self-Assembled Skin Substitute Using a Decellularized Dermal Matrix Grafted on Mice.  Tissue Eng Part A, 23 (7-8), p. 313-322, 2017, ISSN: 1937-3341.

Jacobsen B, Larouche D, Rochette-Drouin O, Ploug M, Germain L. Expression of C4.4A in an In Vitro Human Tissue-Engineered Skin Model.  Biomed Res Int, 2017 , p. 2403072, 2017.

Bourget JM., Zegdi R., Lin J., Wawryko P., Merhi Y., Mao J., Xu T., Fu Y., Ostara Merkel N., Wang L., Germain L., Zhang Z., Guidoin R. Correlation between structural changes and acute thrombogenicity in transcatheter pericardium valves after crimping and balloon deployment. Morphology, 2016.

Piaceski AD., Larouche D., Bisson F., Ghani K., Caruso M., Germain L. Strategies integrating gene therapy and tissue engineering into the development of treatments for Recessive Dystrophic Epidermolysis Bullosa. Epidermolysis Bullosa (EB): Prevalence, Clinical Manifestations and Management. Édition Nova Publisher inc. Chapitre 5, p. 77-114, 2016, Invited.

Bourget JM., Laterreur V., Gauvin R., Guillemette MD., Miville-Godin C., Mounier M., Tondreau MY., Tremblay C., Labbé R., Ruel J., Auger FA., Veres T., Germain L., Microstructured human fibroblast-derived ECM scaffold for vascular media fabrication. Journal of Tissue Engineering and Regenerative Medicine, 2016.

Guidoin R., Fu Y., Li B., Weerasena N., Bourget JM., Paynter R., Li X., Lin J., Wang Lu, Qin B., Guzman R., Desaulniers D., Germain L., Zhang Z. The ROVT Elan valved Biplex conduits for the reconstruction of the right ventricular outflow tract. Journal of Long-Term Effects of Medical Implants, 2016.

Couture C, Zaniolo K, Carrier P, Lake J, Patenaude J, Germain L, Guerin SL. The tissue-engineered human cornea as a model to study expression of matrix metalloproteinases during corneal wound healing.  Biomaterials, 78 , p. 86-101, 2016, ISSN: 0142-9612

Kim DH., Hyun DJ., Piquette R., Beaumont C., Germain L., Larouche D. 27.12-MHz Radiofrequency Ablation for Benign Cutaneous Lesions. BioMed Research International, In : Lasers and Energy Devices for the Skin: Conventional and Unconventional Use. (2016), 2016.

Couture C., Zaniolo K., Carrier P., Lake J., Patenaude J., Germain L., Guérin SL. The tissue-engineered human cornea as a model to study expression of matrix metalloproteinases during corneal wound healing, Biomaterials, (78) ; 86-101, 2016.

Larouche D, Cantin-Warren L, Desgagne M, Guignard R, Martel I, Ayoub A, Lavoie A, Gauvin R, Auger FA, Moulin VJ, Germain L. Improved Methods to Produce Tissue-Engineered Skin Substitutes Suitable for the Permanent Closure of Full-Thickness Skin Injuries.  Biores Open Access, 5 (1), p. 320-329, 2016, ISSN: 2164-7844.

Li B., Liu B., Fu Y., Bondarenko O., Verdant A., Rochette-Drouin O., Lin J., Bourget JM., Guzman R., Wang L.,. Zhang Z, Douville Y., Germain L., Jing Z., Guidoin R. A floating thrombus anchored at the proximal anastomosis of a woven thoracic graft mimicking a genuine aortic dissection. Journal of Long-Term Effects of Medical Implants, 25(3):179-200, 2015.

Bourget JM., Gauvin R., Duchesneau D., Rémy M., Auger FA. Germain L. Potential of Newborn and Adult Stem Cells for the Production of Vascular Constructs using the Living Tissue Sheet Approach. BioMed Research International, special issue: New Biomaterials in Drug Delivery and Wound Care. Hindawi Publishing Corporation, 10 pages, vol 2015.

Beaudoin Cloutier C., Guignard R., Bernard G., Gauvin R., Lavoie A., Lacroix D., Moulin VJ., Germain L., Auger FA. Production of a Bilayered Self-Assembled Skin Substitute Using a Tissue-Engineered Acellular Dermal Matrix. Tissue Engineering Part C. 2015. Dec, 21(12),: 1297-1305, 2015..

Vallières K., Laterreur V., Tondreau MY., Ruel J., Germain L., Fradette, J. Auger FA. Human adipose-derived stromal cells for the production of completely autologous self-assembled tissue-engineered vascular substitutes, Acta biomaterialia. Sep 15;24:209-19, 2015.

Tondreau MY, Laterreur V., Gauvin R., Vallières K., Bourget JM., Lacroix D., Tremblay C., Germain L., Ruel J., Auger FA. Mechanical properties of endothelialized fibroblast-derived vascular scaffolds stimulated in a bioreactor, Acta biomaterialia (AB-14-1906R1), 18 : 176–185, 2015.

Bisson F., Paquet C., Bourget J.-M., Zaniolo K., Rochette P.J., Landreville S., Damour O., Boudreau F., Auger, F.A., Guérin S.L., Germain L. Contribution of Sp1 to Telomerase Expression and Activity in Skin Keratinocytes Cultured With a Feeder Layer. Journal of Cellular Physiology, 230(2) : 308-317, 2015.

Kim DH., Lavoie A., Ratté G., Beaumont C., Germain L., Larouche D. Effect of 27-MHz radiofrequency on hair follicles: Histological evaluation of skin treated ex vivo. Dermatologic surgery. 41(4):466-72, 2015.

Tremblay C., Ruel J., Bourget J.M., Laterreur V., Vallières K., Tondreau M.Y., Lacroix D., Germain L., Auger F.A. A new construction technique for tissue-engineered heart valves using the self-assembly method. Tissue engineering Part C Methods, 20(11):905-915, nov 2014.

Hayward C.J., Fradette J., Morissette Martin P., Guignard R., Germain L., Auger F.A. Using human umbilical cord cells for tissue engineering: a comparison with skin cells. Differentiation, 87(3-4):172-181, aug 2014.

Dubé J., Bourget J.M., Gauvin R., Lafrance H., Roberge C.J., Auger F.A., Germain L. Progress in developing a living human tissue-engineered tri-leaflet heart valve assembled from tissue produced by the self-assembly approach. Acta Biomaterialia, 10(8):3563-70, 2014.

Laterreur V., Ruel J., Auger F.A., Vallières K., Tremblay C., Lacroix D., Tondreau M., Bourget JM., Germain L. Comparison of the direct burst pressure and the ring tensile test methods for mechanical characterization of tissue-engineered vascular substitutes. Journal of the mechanical behavior of biomedical materials, 34:253-63, 2014.

Giasson C.J., Deschambeault A., Carrier P., Germain L. Adherens junction proteins are expressed in collagen corneal equivalents produced in vitro with human cells. Molecular Vision, 20:386-94, 2014.